In reality there are still people in Indonesia who view Children with Special Needs inappropriately. Multi Disabilities Visual Impairment or MDVI is a complex disorder that is experienced by someone with visual limitations accompanied by disturbances in other aspects or organs which are also known as multiple disabilities. Special education teachers as well as Islamic Religious Education teachers use several learning methods by adjusting the circumstances and needs of students, using more of the sensory functions of students' hearing and touch during the learning process. This study aims to determine the application of learning to pray in the subject of Islamic Religious Education (PAI) in children with visual impairment multi-disabilities class 2-A SLB Pajajaran Bandung City using the demonstration method. This research used a qualitative approach with a case study method. The results of the study: Planning according to the lesson plan, applying the prayer learning method using direct instruction, the teacher provides an explanation of new concepts or skills with the aim of assisting students in learning basic skills and obtaining information step by step. Evaluation of learning using oral tests, and practice (actions). The oral test is carried out during the practice of reciting the prayer readings. In the form of prayer movement tests the teacher carries out learning evaluations in the form of practice (actions), direct physical contact with students. The learning difficulty factor experienced is in receiving stimulation or information through the sense of sight, so that it utilizes other senses in receiving stimulation or information. Cognitive learners accept that learning needs to be repeated and the learning difficulties experienced also lie in the motor which tends to be slower when compared to normal children in general. Several recommendations were given to schools, teachers, educational institutions and students, for future researchers to develop research on similar education by using other variables or on other subjects.