The Covid-19 pandemic that has been going on since early 2020 has made health an important issue in the Indo-Pacific Region. One of the actors developing health security in the Indo-Pacific region is QUAD (Quadrulateral Security Dialogue), a dialogue platform between the United States, Australia, Japan and India. This article aims to explain Indonesia's prospects in the field of health security in the Indo-Pacific. This article uses the concept of Health Security and regional security complex theory (rsct) and qualitative methods. Since the pandemic, QUAD has also focused on developing and procuring the Covid-19 vaccine. In this cooperation scheme, India is the country supplying the vaccine, the United States and Japan are donors, and Australia is in charge of distributing the Covid-19 vaccine. Currently, Indonesia has succeeded in developing a Covid-19 vaccine. In the context of health security in the Indo-Pacific, Indonesia's success provides an opportunity for Indonesia to play a more active role in health security issues and support QUAD's role as a vaccine supplier in the region.